The Consumer Justice Foundation Alerts Public to Study Showing that Addition of Valproic Acid (a.k.a. Depakote) to Psychotic Medications Leads to Significant Weight Gain

(PRWEB) February 22, 2012

The Consumer Justice Foundation, a for-profit corporation whose team of professional consumer advocates provide free online educational resources to the public that alert them to the potential risks and dangers presented by certain prescription medications, hereby alerts the public to the results of a recently published study that concludes that the introduction of valproic acid, which is the active ingredient in Depakote to medications already being used by patients taking psychotic drugs can lead to significant weight gain.

This study, which was performed by researchers at Vanderbilt University and led by Dr. Herbert Meltzer, reviewed data concerning patients who suffered from schizophrenia and bipolar disorder who were using medications that included olanzapine and risperidone. Each group was split and one half of the patients were given an additional dose of valproic acid in order to stabilize their moods. Valproic acid is the active ingredient in the anticonvulsant medication known as Depakote.

According to the abstract of the study that was published in Family Practice News, every one of those taking olanzapine plus valproate experienced significant weight gains, whereas the weight gain occurred in 60% of those taking olanzapine alone. In addition, those using risperidone and valproic acid saw 15 percent of subjects experience what was described as significant weight gain. The full study was published in the January 2012 edition of the Journal of Clinical Psychology.

At each visit, obtain both weight and body mass index. Measure waist circumference at least once a year, and provide counseling on diet and exercise, said Dr. Christoph U. Correll of the Zucker Hillside Hospital at a recent psychopharmacology update sponsored by the American Academy of Child and Adolescent Psychiatry.

About the Consumer Justice Foundation

The Consumer Justice Foundation, whose Web site is located at, is a public resource that’s been built and maintained by a group of concerned professionals who want to provide general information for consumers regarding the potential dangers involved with the use of Depakote while pregnant. This resource is not to be considered as medical or legal advice, which should only be dispensed by a licensed medical doctor or a Depakote lawyer.


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